Program “Personalized Oncology 2019” Conference

Venue: University Hospital Basel, Zentrum für Lehre und Forschung (ZLF), Hebelstrasse 20, 4031 Basel map

Sunday, 23.06.2019

14:00Registration, Poster setup
15:15 Welcome
15:30Tandem Keynote:
Michael Hall (University of Basel)
Mechanisms of Evasive Resistance in HCC


Andreas Neubauer (University of Marburg)
Precision oncology: help, hope and hype: Genomic profile for every cancer?
17:00Flash talks:
Phil Cheng (University Hospital Zurich)
Andreas Dzung (University Hospital Zurich)
Chen Li (ETH Zurich)
Filipe Martins (EPFL)
Dirk Mossmann (University of Basel)
Corinne Stoffel (University Hospital Zurich)
Nami Sugiyama (University of Basel)
Lorenz Waldmeier (NBE-Therapeutics)
17:30 Poster session & Reception
18:30Barbecue @ ZLF courtyard
21:30 End

Monday, 24.06.2019

Session I: “Predicting Outcomes: from Biology to Artificial Intelligence” (Chair: Olivier Michielin)
08:45

09:05
Andreas Trumpp (Deutsches Krebsforschungszentrum)
Stem cells features in cancer
Q&A
09:15

09:35
Mark Rubin (University of Bern)
Precision Oncology for Advanced Prostate Cancer Reveals a Disease in Transition
Q&A
09:45

10:05
Peter Campbell (Wellcome Sanger Institute)
Interrogating the architecture of cancer genomes
Q&A
10:15 Coffee break
10:45

11:05
Lillian Siu (University of Toronto)
Multi-omic dynamic evaluations in patients receiving Immunotherapy
Q&A
11:15 Short talk: Eva Dazert (University of Basel)
Cracking the HCC code - An OMICS map of liver cancer to understand its development and therapy response
11:30 Short talk: Ataman Sendoel (University of Zurich)
The translational landscape of cancer
11:45 Panel discussion
12:15 Lunch & Poster session

     

Session II: “Treatments, Resistance, and Combination of Therapies” (Chair: Alessandra Curioni Fontecedro)
14:00

14:20
Roger Lo (University of California Los Angeles)
Strategies to suppress resistance in melanoma
Q&A
14:30


14:50
Mark Rubinstein (University of South Carolina)
Augmenting anti-tumor immunity with the combination of IL-15/IL-15Ra complexes and PD-1/PD-L1 blockade
Q&A
15:00

15:20
Anna Obenauf (Research Institute of Molecular Pathology)
Understanding tumor evolution during cancer progression and therapy
Q&A
15:30 Coffee break
16:00


16:20
Daniel Peeper (The Netherlands Cancer Institute)
Rational cancer & immune cell therapy combinations - a functional genomics approach

Q&A
16:30 Short talk: Ana Luisa Correia (University of Basel)
NK cells sustain breast cancer dormancy in the liver
16:45 Short talk: Daniel Zingg (The Netherlands Cancer Institute)
Oncogenic signaling of FGFR2 relies on truncation of its C-terminal tail
17:00 Panel discussion
17:30Transfer to Elisabethenkirche Basel map
18:15
Apero @ Elisabethenkirche
19:00Personalized Oncology in Switzerland @ Elisabethenkirche: Olivier Michielin (University Hospital Lausanne), Mohamed Bentires-Alj (University of Basel), Andreas Wicki (Kantonsspital Baselland), Mitch Levesque (University Hospital Zurich)
19:45 Conference Dinner @ Elisabethenkirche map
23:30End

Tuesday, 25.06.2019

Session III: “From Personalized Avatars and Disease Models to Novel Trial Methods” (Chair: Mitch Levesque)
08:15


08:35
Olli Kallioniemi (Karolinska Institute)
Functional drug testing and precision systems medicine: from leukemias to solid tumors
Q&A
08:45

09:05
Meenhard Herlyn (The Wistar Institute)
Strategies for targeted and immune therapy in melanoma
Q&A
09:15


09:35
Jonas Nilsson (University of Gothenburg)
Personalized immune avatars and genetic analyses to support clinical decision making for patients with skin and uveal melanoma
Q&A
09:45 Coffee break
10:15


10:35
Lars Hemkens (Basel Institute for Clinical Epidemiology & Biostatistics / Universitätsspital Basel)
Disruptive clinical trial technologies for systematic innovation in oncology
Q&A
10:45Short talk: Stefano Annunziato (The Netherlands Cancer Institute)
Comparative oncogenomics identifies combinations of driver genes and drug targets in BRCA1-mutated breast cancer
11:00Short talk: Atul Sethi (University of Basel)
Single cell RNA sequencing reveals tumor heterogeneity and pre-existing chemo-resistant cells in breast cancer
11:15 Coffee break
11:45Tandem keynote and conference summary:
Markus Heim (University of Basel)
Personalised Oncology for Hepatocellular Carcinoma: Alfa-fetoprotein. And a long way to go.

Douglas Hanahan (EPFL Lausanne)
Future visions for Personalized (Precision) Oncology, and a case study in co-targeting hallmarks of cancer
13:15Poster Award, closing
13:30Adjourn
14:00Ethics and the Future of Health (Partner event by BaselArea.swiss)

DayOne Masterclass on exponential Ethics with Dr. Nicoletta Iacobacci (Webster University Geneva and Jinan University Guangzhou, China)
        Information and registration on the website
17:30End